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Allele : Erbb3<tm3Cbm> erb-b2 receptor tyrosine kinase 3; targeted mutation 3, Carmen Birchmeier
Primary Identifier  MGI:3835516 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Erbb3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sequences were inserted into a unique Pac1 site located 5' of exons 10 and 11. The human ERBB3 cDNA was ligated in frame into exon 12 using a Bcll site. The targeting vector also contained a neomycin-resistance cassette flanked by loxP sites and exon 17 and downstream sequences. The neomycin-resistance cassette was removed by Cre-recombination in ES cells.
  • mutations:
  • Insertion
  • synonyms:
  • ErbB3<fl>,
  • ErbB3<flox>,
  • ErbB3<flox>,
  • ErbB3<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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