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Allele : Hand2<tm2Eno> heart and neural crest derivatives expressed 2; targeted mutation 2, Eric N Olson

Primary Identifier  MGI:3838372 Allele Type  Targeted
Gene  Hand2 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 1 was replaced with one in which nucleotide substitutions result in the amino acid substitution of glutamic acid, aspartic acid, and glutamic acid for the three arginines at positions 109 to 111. These arginines are necessary for DNA binding activity. An frt flanked neo cassette inserted downstream of exon 1 was removed by germ line, flp mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Hand2<EDE>,
  • Hand2<EDE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele