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Allele : Eef1a1<tm1(Kras*)Arge> eukaryotic translation elongation factor 1 alpha 1; targeted mutation 1, Argiris Efstratiadis
Primary Identifier  MGI:3837679 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence Gene  Eef1a1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene and STOP cassette was inserted along with a constitutively active Kras with the amino acid substitution of glycine with aspartic acid at position 12 (p.G12D) into intron 1. Cre-mediated removal of the STOP cassette is required to achieve expression of the constitutively active Kras.
  • mutations:
  • Insertion
  • synonyms:
  • Eef1a1-Kras*,
  • Eef1a1-Kras*
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele




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