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Allele : Ttr<tm1Kymm> transthyretin; targeted mutation 1, Ken-ichi Yamamura
Primary Identifier  MGI:3838181 Allele Type  Targeted
Attribute String  Null/knockout, RMCE-ready Gene  Ttr
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A null allele was created by replacing the ATG start site within exon 1 with a PGK-neo cassette flanked by lox71 and loxP sites. Besides disrupting the gene, the cassette also serve as an acceptor in recombination mediated cassette exchange. No protein was detected in immunoblot analysis of homozygote livers.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ttr<->,
  • Ttr<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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