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Allele : Tg(tetO-DISC1*)1001Plet transgene insertion 1001, Mikhail Pletnikov
Primary Identifier  MGI:3838645 Allele Type  Transgenic
Attribute String  Epitope tag, Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO-DISC1*)1001Plet
Strain of Origin  C57BL/6 and SJL Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene construct was designed with the myc peptide tagged mutant human DISC1 (disrupted in schizophrenia 1) gene, under the control of tetracycline operator (tetO; also called tetracycline-responsive element (TRE) or tet-operator) sequence and a cytomegalovirus minimal promoter. Founder line 1001, which showed strong expression, was established. A second line, line 70, shows a weak expression of human DISC1.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(TRE-CMVhDISC1),
  • Tg(tetO/CMV-DISC1*)1001Plet,
  • Tg(tetO/CMV-DISC1*)1001Plet,
  • Tg(TRE-CMVhDISC1)
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

16 Publication categories

Trail: Allele




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