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Allele : Cyp1a<tm1.1Bra> cytochrome P450, family 1, subfamily a cluster; targeted mutation 1.1, Christopher A Bradfield
Primary Identifier  MGI:3840319 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp1a
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  An frt flanked neo cassette followed by a loxP site were inserted upstream and a second loxP site was inserted downstream of a cluster of 7 dioxin responsive elements (DRE). These DREs regulate expression of both Cyp1a1 and Cyp1a2. The neo cassette and DRE cluster were then removed by Flp and Cre mediated recombination respectively.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • Cyp1a1/Cyp1a2<tm1.1Bra>,
  • Cyp1a1/Cyp1a2<tm1.1Bra>,
  • DREC<->,
  • DREC<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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