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Allele : Gt(ROSA)26Sor<tm1(SNCA*A53T)Djmo> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Darren Moore
Primary Identifier  MGI:3840598 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  Original reference states that 129/SvJ-derived embryonic stem cells were used.
molecularNote  A targeting vector was designed with an SV40 splice acceptor, a loxP-flanked STOP cassette (PGK-neo and triple SV40 transcriptional termination sequence), a human alpha-synuclein cDNA bearing a familial Parkinson's disease-linked A53T missense mutation (SYNA53T), and a bovine polyadenylation signal.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26-SynA53T<Tg>,
  • ROSA26-SynA53T<Tg>,
  • ROSA26-Syn-A53T,
  • ROSA26-Syn-A53T
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

6 Publication categories

Trail: Allele




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