| Primary Identifier | MGI:3840862 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Map3k3 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A single loxP site was introduced into intron 10 and a floxed neomycin cassette was introduced into intron 11. Cre recombinase was transiently expressed in correctly targeted ES cells to remove the neomycin cassette, leaving exon 11 floxed. Exon 11 encodes the ATP-binding site (K391) essential for the kinase activity of the protein product. |
