Primary Identifier | MGI:3841575 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Fzd10-cre/Esr1*)1Chzh |
Strain of Origin | C57BL/6 x FVB/N | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgenic construct contained a 6.7 kb fragment upstream of the transcriptional start site of the mouse Fzd10 gene followed by a CreERTM cassette carrying a polyA sequence. This construct was injected into fertilized oocytes with five transgenic founders obtained. Expression analysis showed that 3 lines exhibited expression patterns similar to a previously characterized transgenic Fzd10 reporter mouse line. One line was picked for further characterization. |