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Allele : Abcb1a<tm1Kane> ATP-binding cassette, sub-family B member 1A; targeted mutation 1, Susan E Kane

Primary Identifier  MGI:3842696 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Abcb1a
Transmission  Germline Strain of Origin  129S1/SvImJ
Is Recombinase  false Is Wild Type  false
molecularNote  A luciferase cDNA fused in-frame with the noncoding part of exon 2 gene was preceded by a floxed neomycin expression cassette that contained a synthetic polyadenylation sequence to stop transcription. This construct was inserted downstream of exon 2 with an additional loxP site inserted upstream of the exon. Upon cre recombinase mediated excision of exon 2 and the neo cassette, luciferase will be expressed under the control of endogenous locus.
  • mutations:
  • Insertion
  • synonyms:
  • Mdr1a<flox>,
  • Mdr1a<flox>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele