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Allele : Tg(Camk2a-UBB*)3413-1Fwvl transgene insertion 3413-1, FW van Leeuwen

Primary Identifier  MGI:3843483 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Camk2a-UBB*)3413-1Fwvl
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  A transgenic construct containing cDNA encoding the mutant human ubiquitin B, UBB+1 sequence (in the +1 reading frame), under the direction of the mouse Camk2a (calcium/calmodulin-dependent protein kinase II alpha) promoter was injected into fertilized C57BL/6 mouse eggs. Founder line 3413-1 with 13 copies of the transgene was subsequently established. mRNA levels for UBB+1 are 49% of endogenous Ubb mRNA levels.
  • mutations:
  • Insertion
  • synonyms:
  • UBB+1 3413,
  • UBB<+1> 3413,
  • UBB<+1> 3413,
  • UBB+1 3413
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele