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Allele : Prkar1a<tm2Gsm> protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 2, G Stanley McKnight

Primary Identifier  MGI:3845256 Allele Type  Targeted
Attribute String  Conditional ready, Dominant negative Gene  Prkar1a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation results in the amino acid substitution of alanine for glycine at position 324 (G324A) encoded by exon 11. A floxed neo cassette upsteam of exon 11 prevents expression of the dominant negative mutation except following cre mediated removal of the cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • RIalphaB,
  • RIalphaB
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele