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Allele : Mapt<tm3(Hdac2)Jae> microtubule-associated protein tau; targeted mutation 3, Rudolf Jaenisch

Primary Identifier  MGI:3844982 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Mapt
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Coding sequence for the mouse Hdac2 protein was placed in-frame with exon 1 of the gene locus creating a fusion protein containing the first 31 amino-acids of the endogenous locus. A 2-3 fol expression of Hdac2 was confirmed in the CA1 region of the hippocampus by immunohistofluorescence. Hdac2 activity was confirmed by decreased levels of acetylation present in the same region as expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Tau<HDAC2>,
  • Tau<HDAC2>,
  • HDAC2OE,
  • HDAC2OE
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele