Primary Identifier | MGI:3850105 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-PTGS2)17Upme |
Strain of Origin | (C57BL/6J x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The mouse cardiac alpha-myosin heavy chain promoter (Myh6) drives the expression of a human PTGS2 (COX-2) gene including 5' UTR region. The poly (A) signal sequences of human growth hormone were included at the 3' end of the construct. Three copies of the transgene are present in line 17. In addition to line 17, line 12 was also created. |