|  Help  |  About  |  Contact Us

Allele : Dp(XTceal3-Plp1)1Gmh duplication 1, Grace Hobson; duplication, Chr X, Grace Hobson 1
Primary Identifier  MGI:3852180 Allele Type  Targeted
Gene  Dp(XTceal3-Plp1)1Gmh Transmission  Germline
Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2> Is Recombinase  false
Is Wild Type  false
molecularNote  Micer clones MHPN312j24 (NCBIM37, 133123007-133127471) and MHPP264b06 (NCBIM37, 133374577-133383807) and cre mediated recombination were used to generate a tandem head-to-tail duplication of a 260.8 kb region between the two sites and a complete HPRT gene at the junction. The duplication spans from Tceal3 through 9.5 kb distal of Plp1. Presence of a duplication was confirmed in mice by semiquantitative multiplex PCR, Southern blot analysis, and FISH. qRT-PCR indicates an increase in Plp1, Tceal1, Tceal3, Morf4l2 and BC065397 transcript levels at multiple postnatal time points.
  • mutations:
  • Insertion
  • synonyms:
  • Plp1 dup,
  • Plp1 dup,
  • Dp(XMHPN312j24-MHPP264b06)1Tju,
  • Dp(XTceal3-Plp1)1Tju,
  • Dp(XMHPN312j24-MHPP264b06)1Tju,
  • Dp(XTceal3-Plp1)1Tju
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

9 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom