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Allele : Ndufs4<Gt(CB0524)Wtsi> NADH:ubiquinone oxidoreductase core subunit S4; gene trap CB0524, Wellcome Trust Sanger Institute

Primary Identifier  MGI:3866986 Allele Type  Gene trapped
Attribute String  Hypomorph, Reporter Gene  Ndufs4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Sanger Inst. Gene Trap Res.
molecularNote  A gene trap vector inserted into intron 1. A 50% reduction in both encoded mRNA transcript, as well as encoded protein abundance was shown in brain tissue of homozygous mice, resulting in a 25% reduction in protein activity in the hippocampus compared to controls.
  • mutations:
  • Insertion
  • synonyms:
  • Ndufs4<CB0524>,
  • Ndufs4<GT>,
  • Ndufs4<GT>,
  • Ndufs4<CB0524>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele