| Primary Identifier | MGI:3870362 | Allele Type | Gene trapped |
| Attribute String | Hypomorph | Gene | Cep290 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Sanger Inst. Gene Trap Res. |
| description | Phenotypic Similarity to Human Syndrome: Nephronophthisis (J:212182) |
| molecularNote | The gene was disrupted by a gene trap insertion within intron 23 and resulted in a hypomorphic mutation. The gene trap contains a beta-galactosidase/neomycin reporter gene with a ribosomal reentry site (IRES) followed by a poly(A) tail. Genomic DNA PCR confirmed the insertion of the gene trap and localized it to 3.308 kb downstream of exon 24. |
