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Allele : Rest<Gt(D047E11)Wrst> RE1-silencing transcription factor; gene trap D047E11, German Gene Trap Consortium

Primary Identifier  MGI:3873420 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Rest
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap vector inserted in the intron between non-coding exon 1ac and the first coding exon, exon 2. The construct contains a splice acceptor site upstream of a promoter-less beta-galactosidase and neomycin gene fusion (beta-geo) and a polyadenylation sequence. Beta-geo expression in this line is under the control of endogenous regulatory elements for this gene. Loss of both enndogenous protein and messenger RNA was observed.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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10 Publication categories

Trail: Allele