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Allele : Cftr<tm1Hgu> cystic fibrosis transmembrane conductance regulator; targeted mutation 1, MRC Human Genetics Unit

Primary Identifier  MGI:1856710 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cftr
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An insertion of a vector into intron 9 that included exon 10 interrupted by a neomycin selection gene. RT-PCR analysis on tissues derived from homozygous mice demonstrated that a low level of wild-type transcript was produced from this allele by exon skipping (J:20037).
  • mutations:
  • Insertion
  • synonyms:
  • Cftr<m1Hgu>,
  • cf,
  • cftr<m1HGU>,
  • Cftr<TgH(neoim)1Hgu>,
  • cf,
  • EDI,
  • cftr<m1HGU>,
  • Cftr<TgH(neoim)Hgu>,
  • EDI,
  • Cftr<m1Hgu>,
  • Cftr<TgH(neoim)1Hgu>,
  • Cftr<TgH(neoim)Hgu>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

32 Publication categories