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Allele : Hnf1a<em1Yumia> HNF1 homeobox A; endonuclease-mediated mutation 1, Miao Yu

Primary Identifier  MGI:7562174 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Hnf1a
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRIPSR/cas9 mediated recombination created 3 nucleotide changes (GAAG to CGAA) resulting in a substitution mutation of lysine 117 to glutamic acid. The homologous mutation in humans is associated with maturity-onset diabetes of the young 3.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • K117E,
  • K117E
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele