Primary Identifier | MGI:7562174 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Hnf1a |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRIPSR/cas9 mediated recombination created 3 nucleotide changes (GAAG to CGAA) resulting in a substitution mutation of lysine 117 to glutamic acid. The homologous mutation in humans is associated with maturity-onset diabetes of the young 3. |