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Allele : Gabpb2<em1(IMPC)Tcp> GA repeat binding protein, beta 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7512906 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Gabpb2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GGGATCTTACACGGATTGAA targeting the 5' side and ATGGCCTCGTACACGCAACC targeting the 3' side of a critical region (ENSMUSE00000494767 and ENSMUSE00001271433). This resulted in a 3959-bp deletion of Chr3 from 95107302 to 95111260 (GRCm39) introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele