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Allele : Tg(Thy1-EGFP)MJrs transgene insertion M, Joshua R Sanes

Primary Identifier  MGI:3766828 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Thy1-EGFP)MJrs
Strain of Origin  (C57BL/6J x CBA)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The Thy1-GFP transgene was designed with a modified regulatory region of the "murine thy1.2 gene" (extending from the promoter to the intron following exon 4, excluding exon 3 and its flanking introns) upstream of an enhanced green fluorescent protein (EGFP) sequence. Line M was subsequently established and analyzed. Expression of EGFP is detected primarily in mossy fibers in internal granule layer of the cerebellum (10-80% incidence). Less than 10% of all motor axons, retinal ganglion cells, lumbar dorsal root ganglion, and cortex express EGFP, with no reported expression in other tested neuronal tissues.
  • mutations:
  • Insertion
  • synonyms:
  • GFP line-M,
  • GFP-M,
  • GFP line-M,
  • Thy1-GFP line M,
  • Thy1::GFP-M,
  • Thy1-GFP/M,
  • GFP-M,
  • Thy1-GFP line M,
  • Thy1-GFPM,
  • Thy1-GFP/M,
  • Thy1::GFP-M,
  • Thy1-GFPM
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

213 Publication categories

Trail: Allele