Primary Identifier | MGI:6314809 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Mynn |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
Is Recombinase | false | Is Wild Type | false |
Project Collection | IMPC |
molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AAATCAATCGTAACAGTGAA and GTAATCATTAACTAACATAA, which resulted in a 424 bp deletion beginning at Chromosome 3 position 30,608,751 bp and ending after 30,609,174 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000399042 (exon 4) and 264 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 354 and early truncation 22 amino acids later. |