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Allele : Apoc3<tm1Unc> apolipoprotein C-III; targeted mutation 1, University of North Carolina

Primary Identifier  MGI:1857128 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apoc3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exon 4 was replaced with a neomycin selection cassette. Northern blot analysis indicated that no stable transcript was produced from this allele in homozygous mice. Expression of the Apoa1 and Apoa4 genes that lie in close proximity to Apoc3 are reduced by half in the intestine of homozygotes but not in the liver.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • apoc3-,
  • apoc3-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele