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Allele : Cyp19a1<tm1Esi> cytochrome P450, family 19, subfamily a, polypeptide 1; targeted mutation 1, Evan R Simpson

Primary Identifier  MGI:2154536 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp19a1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Metabolic Syndrome in mice homozygous for Apoetm1Unc and Cyp19a1tm1Esi (J:184647)
molecularNote  Insertion of a neomycin resistance cassette into exon 9 disrupted the gene. Aromatase activity was not detected in ovaries of 12 week old homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ArKO,
  • ArKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

64 Publication categories

Trail: Allele