Primary Identifier | MGI:2154536 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cyp19a1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Metabolic Syndrome in mice homozygous for Apoetm1Unc and Cyp19a1tm1Esi (J:184647) |
molecularNote | Insertion of a neomycin resistance cassette into exon 9 disrupted the gene. Aromatase activity was not detected in ovaries of 12 week old homozygous mutant mice. |