| Primary Identifier | MGI:5490035 | Allele Type | Targeted |
| Attribute String | Hypomorph, Inserted expressed sequence | Gene | Tgfb1 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES stem cell line is an unspecified albino C57BL/6 |
| molecularNote | A construct, consisting of a loxP site, the 3' UTR from Fos, two copies of a transcriptional insulator from the chicken beta globin gene, a neo cassette, a second loxP site and the 3' UTR from bovine GH1, replaced the 3' UTR of the gene. The mRNA produced by this allele is unstable and results in a lower level of expression compared to wild-type littermates. |
