Primary Identifier | MGI:4417942 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Foxa2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neo cassette was inserted upstream of exon 3 and a loxP site followed by a modified exon 3 was inserted downstream of exon 3. The modification results in the amino acid substitution of alanine for threonine at position 156 (T156A). Cre mediated recombination removed the neo cassette. |