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Allele : Srgap2<Gt(XH102)Byg> SLIT-ROBO Rho GTPase activating protein 2; gene trap XH102, BayGenomics

Primary Identifier  MGI:4126449 Allele Type  Gene trapped
Attribute String  Hypomorph, Reporter Gene  Srgap2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap vector inserted between exons 2 and 3 of the gene. Cortical cells from homozygous mice show a ~90% reduction in the level of expressed normal transcript and protein from this allele. The mutation results in the production of a fusion protein composed of the first 22 aa of SRGAP2 and beta-Geo.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele