Primary Identifier | MGI:4128148 | Allele Type | Gene trapped |
Gene | Huwe1 | Transmission | Cell Line |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Trapped gene association determined by genome coordinate overlap and strand. Trap vector is inserted into intron 4 of the gene. Immunoblot on ES cells demonstrates absence of Huwe1 protein expression. Insertion abolish the splicing of the exons that code for the essential HECT domain. |