Primary Identifier | MGI:6199674 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Vav1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced G to A transition at base pair 57,297,122 (v38) on chromosome 17, or base pair 18,044 in the GenBank genomic region NC_000083. The mutation corresponds to residue 621 in the mRNA sequence NM_011691 within exon 5 of 27 total exons. The mutation results in a glutamic acid to lysine substitution at amino acid 175 (E175K) in the VAV1 protein. |