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Allele : Vav1<m2Btlr> vav 1 oncogene; mutation 2, Bruce Beutler

Primary Identifier  MGI:6199674 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Vav1
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced G to A transition at base pair 57,297,122 (v38) on chromosome 17, or base pair 18,044 in the GenBank genomic region NC_000083. The mutation corresponds to residue 621 in the mRNA sequence NM_011691 within exon 5 of 27 total exons. The mutation results in a glutamic acid to lysine substitution at amino acid 175 (E175K) in the VAV1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • plain_sight,
  • plain_sight
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories