Primary Identifier | MGI:2663941 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bcl11a |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.4 kb region containing exon 1 was deleted and replaced with a PGK-neo cassette via homologous recombination. Absence of gene expression was confirmed by Northern blot and immunohistochemical analysis of homozygous mutant brains. |