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Allele : Tg(H2-Ab1-HLA-DPB1)1Lone transgene insertion 1, Yu Chun Lone
Primary Identifier  MGI:5494677 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(H2-Ab1-HLA-DPB1)1Lone
Strain of Origin  C57BL/6 x DBA/2 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene contains a full length cDNA encoding the 04:01 variant of the beta chain of the human major histocompatibility complex (MHC) class II DP receptor (HLA-DPB1*4:01) downstream of the promoter of the mouse histocompatibility 2, class II antigen A, beta 1 (H2-Ab1) locus. The human cDNA is followed by the mouse H2-Ab1 3' noncoding sequence. Mice bearing this transgene in combination with Tg(H2-Aa-HLA-DPA1)1Lone express a human HLA-DPalpha103/DPbeta401 complex that is specifically recognized by the anti-HLA-DP monoclonal antibody B72.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(HLA-DPB401),
  • Tg(HLA-DPB401)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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