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Allele : Tg(CAG-Fgfr3*K650E,-EGFP)10Jheb transgene insertion 10, Jean Hebert
Primary Identifier  MGI:6108317 Allele Type  Transgenic
Attribute String  Conditional ready, Inserted expressed sequence, Reporter Gene  Tg(CAG-Fgfr3*K650E,-EGFP)10Jheb
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The transgenic construct was designed with a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), a loxP-flanked STOP cassette, the mouse Fgfr3 (fibroblast growth factor receptor 3) cDNA containing a lysine to glutamic acid substitution at residue 650 (K650E) rendering Fgfr3 constitutively active, followed by an IRES-eGFP fluorescent protein sequence.
  • mutations:
  • Insertion
  • synonyms:
  • FGFR3-GOF,
  • FGFR3-GOF
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele




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