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Allele : Tg(IGH@*)SALed transgene insertion SA, Philip Leder

Primary Identifier  MGI:3802806 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(IGH@*)SALed
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A recombined human mu heavy chain immunoglobulin gene was used in the construction of a transgene. Downstream of the last mu constant region exon, two deletions eliminated the cleavage /poly(A) addition signal so that only the membrane bound form IgM would be expressed. Two transgene lines were created, SA and SD, with the SA line having higher expression. Transgene expression was detected by RT-PCR in the spleen and brain of both transgenic lines.
  • mutations:
  • Insertion
  • synonyms:
  • TG SA,
  • human mIgM,
  • human mIgM,
  • TG SA
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele