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Allele : Eif2ak3<tm1Dron> eukaryotic translation initiation factor 2 alpha kinase 3; targeted mutation 1, David Ron

Primary Identifier  MGI:2177666 Allele Type  Targeted
Attribute String  Null/knockout Gene  Eif2ak3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced 1.6 kb of DNA containing the transmembrane domain. Northern blot analysis demonstrated that at least 10-fold less transcript was produced from this allele that the wild-type. However, western blot analysis on cells derived from homozygous mice confirmed that no detectable protein was expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • perk -,
  • perk -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

32 Publication categories

Trail: Allele