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Allele : Nlrp3<m4Btlr> NLR family, pyrin domain containing 3; mutation 4, Bruce Beutler

Primary Identifier  MGI:4999611 Allele Type  Chemically induced (ENU)
Gene  Nlrp3 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU mutagenesis induced a T to C transition at 59369377 bp or position 2672 of the Nlrp3 transcript in exon 6 of 10 total exons (Genbank record NM_145827). The mutation is located in the fifth coding exon and results in a cysteine to arginine substitution at amino acid 816 (C816R).
  • mutations:
  • Single point mutation
  • synonyms:
  • ND7,
  • ND7
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele