Primary Identifier | MGI:4999611 | Allele Type | Chemically induced (ENU) |
Gene | Nlrp3 | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU mutagenesis induced a T to C transition at 59369377 bp or position 2672 of the Nlrp3 transcript in exon 6 of 10 total exons (Genbank record NM_145827). The mutation is located in the fifth coding exon and results in a cysteine to arginine substitution at amino acid 816 (C816R). |