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Allele : Igs2<em23(CAG-EGFR*T790M*L858R)Gpt> intergenic site 2; endonuclease-mediated mutation 23, GemPharmatech Co., Ltd
Primary Identifier  MGI:7300636 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inserted expressed sequence Gene  Igs2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JGpt
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting inserted a CAG promoter, floxed STOP cassette, and human gene coding sequence with mutation that results in the amio acid substitution of threonine with methionine at position 790 (T790M) and leucine with arginine at position 858 (L858R).
  • mutations:
  • Insertion
  • synonyms:
  • Igs2<em1Cin(CAG-LSL-EGFR(T790M L858R))>,
  • Igs2<em1Cin(CAG-LSL-EGFR(T790M L858R))>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele




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