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Allele : Col1a1<tm1(tetO-Vegfc)Mmul> collagen, type I, alpha 1; targeted mutation 1, Matthias Muller
Primary Identifier  MGI:5704365 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae (J:98920). This allele was generated with Col1a1tm13(neo/hygro*)Jae.
molecularNote  A construct containing the tetracycline responsive element, comprising seven tandem copies of the 19-base pair tetracycline operator (tetO), followed by cDNA encoding vascular endothelial growth factor C was introduced by FLP recombinase-mediated cassette exchange (RCME) into the frt docking site of Col1a1tm13(neo/hygro*)Jae in KH2 ES cells.
  • mutations:
  • Insertion
  • synonyms:
  • Col1a1<tm1(tetO-VEGFC)Biat>,
  • Col1a1<tm1(tetO-VEGFC)Biat>
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1 Feature

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Genome

1 Expresses

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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