Primary Identifier | MGI:2681515 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ghr |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced genomic sequences including exons 7, 8a and 8. Northern blot analysis demonstrated that no detectable transcript was expressed from this allele, and western blot analysis confirmed that no encoded protein was present in hepatic microsomal membrane extracts derived from homozygous mice. |