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Allele : Ghr<tm1Arge> growth hormone receptor; targeted mutation 1, Argiris Efstratiadis

Primary Identifier  MGI:2681515 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ghr
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced genomic sequences including exons 7, 8a and 8. Northern blot analysis demonstrated that no detectable transcript was expressed from this allele, and western blot analysis confirmed that no encoded protein was present in hepatic microsomal membrane extracts derived from homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ghr-,
  • Ghr-,
  • Ghr<ex7-8>,
  • Ghr<ex7-8>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories