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Allele : Kpna2<em2Alfon> karyopherin subunit alpha 2; endonuclease-mediated mutation 2, Alfonso Gutierez-Adan

Primary Identifier  MGI:7512793 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Kpna2
Strain of Origin  (C57BL/6 x CBA)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an 8-bp (AACCTGTT) deletion in exon 2 predicted to result in a frameshift and early chain termination due to a premature stop codon and generate a 31 amino acid protein instead of the 529 amino acid wild-type protein. This allele represents line 7.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Kpna2<-7>,
  • Kpna2<-7>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories