Primary Identifier | MGI:7512793 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Kpna2 |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated an 8-bp (AACCTGTT) deletion in exon 2 predicted to result in a frameshift and early chain termination due to a premature stop codon and generate a 31 amino acid protein instead of the 529 amino acid wild-type protein. This allele represents line 7. |