Primary Identifier | MGI:4354162 | Allele Type | Chemically induced (ENU) |
Gene | Srr | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6JJcl | Is Recombinase | false |
Is Wild Type | false | Project Collection | RIKEN GSC ENU Project |
molecularNote | A T to A transversion was induced at the start of exon 9 resulting in a nonsense mutation (Tyr269Stop). Western blot analysis indicated absence of protein expression in the brains of homozygous mice. D-serine production assays indicated absence of protein activity in preparations from whole brain, hippocampus, and frontal cortex from homozygous mice. |