| Primary Identifier | MGI:4354167 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Apoe-Fgf21)1Sakl |
| Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mouse promoter was used to drive liver-specific expression of the mouse cDNA. Two lines were created (1 and 2) that result in 50-fold, and 150-fold, respectively, higher expression of the transcript compared to in wild-type mice. The two lines exhibit virtually identical changes in fasting serum beta-hydroxybutyrate, triglyceride, total cholesterol, glucose, and insulin concentrations. Line 1 was selected as the representative line. |
