| Primary Identifier | MGI:4354193 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Tyr-BRAF*V600E)476Fgh |
| Strain of Origin | (C57BL/6J x CBA)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mouse promoter was used to drive melanocyte-specific expression of the human cDNA containing the amino acid substitution of glutamic acid for valine at position 600 (V600E). This cDNA was cloned from a melanoma line. Four founders were generated and two lines examined (470 and 476). Line 470 exhibits a 3-fold high transcript expression compared to line 476. |
