Primary Identifier | MGI:4354204 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Casq2 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A mutation was introduced into exon 1 altering codon 33 so that it encodes glutamine rather than arginine (R33Q). A loxP site and an frt flanked PGK-neomycin were inserted following exon 1. Male mice were bred to female mice expressing flp recombinase in order to remove the selection cassette. |