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Allele : Grm5<tm1.1Kksz> glutamate receptor, metabotropic 5; targeted mutation 1.1, Karen K Szumlinski

Primary Identifier  MGI:4353518 Allele Type  Targeted
Gene  Grm5 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The open reading frame was replaced with one containing two point mutations (TTC to CGC) in exon 8. These mutations result in an amino acid substitution of arginine for phenylalanine at position 1128 (F1128R). An upstream floxed neo was removed by germ line, cre mediated recombination. This mutation is expected to reduce Homer binding.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • mGluR5<F1128R>,
  • Grm5<R>,
  • Grm5<R>,
  • mGluR5<F1128R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele