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Allele : Arx<tm3Kki> aristaless related homeobox; targeted mutation 3, Kunio Kitamura

Primary Identifier  MGI:4359176 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Arx
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with one in which nucleotide substitutions result in the amino acid substitution of proline with leucine at position 355 in the encoded protein (p.P355L), mimicking a mutation found in some X-linked lissencephaly patients. A neomycin resistance gene cassette was inserted into intron 2.
  • mutations:
  • Intragenic deletion,
  • Nucleotide substitutions
  • synonyms:
  • Arx<P355L>,
  • Arx<PL>,
  • Arx<PL>,
  • Arx<P355L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele