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Allele : Pik3cb<tm1.1Ehi> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; targeted mutation 1.1, Emilio Hirsch

Primary Identifier  MGI:4358053 Allele Type  Targeted
Gene  Pik3cb Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced with one in which a point mutation results in an amino acid substitution of arginine for lysine at position 805 (K805R). A floxed neo cassette was used for selection purposes and removed by germ line, cre-mediated recombination. The predicted protein is expected to be a kinase dead version.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • PIK3CB<K805R>,
  • PIK3CB<K805R>,
  • Pik3cb<K805>,
  • PIK3CB<805R>,
  • PIKbeta<KD>,
  • PIKbeta<KD>,
  • PIK3CB<805R>,
  • Pik3cb<K805>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele