| Primary Identifier | MGI:4357948 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(EIF1AX-PMS2*)685Tcar |
| Strain of Origin | (C57BL/6 x SJL/J)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human EIF1AX (eukaryotic translation initiation factor 1A, X-linked; elongation factor 1A) promoter drives expression of the "Morphogene" transgene which encodes a truncation of the human PMS2 (PMS2 postmeiotic segregation increased 2 (S. cerevisiae)) gene at codon 134 (hPMS2-134). The vector also contains the bovine growth hormone polyA sequence. The transgenic cassette was injected into (C57BL/6 x SJL/J)F2 mouse embryos. Line 685 was established. |
