Primary Identifier | MGI:4361573 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(ACTB-Abl1*K290R)1Spg |
Strain of Origin | (C57BL/6 x CBA)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human beta actin (ACTB) promoter drives expression of the Type IV Abl1 cDNA transcript. A point mutation causing a K290R substitution in the tyrosine kinase domain ATP binding domain. The vector was introduced to B6CBAF2 embryos. |