| Primary Identifier | MGI:4361633 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Ins2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting construct contains loxP sites flanking the mouse Ins2 gene. An Frt-flanked Neo cassette was inserted after the Ins2 exon 3 before the loxP site. The construct was injected into ES cells to modify the endogenous locus through homologous recombination. Mice expressing this allele were generated and subsequently crossed to 129S4/SvJaeSor-Gt(ROSA)26Sortm1(FLP)Dym/J mice to delete the Neo cassette. |
